MAMEWorld Forums - The Loony Bin - Re: Need advice on a new desktop case

My suggestion would be to go with Fractal Design.

Their "Define" series are visually gorgeous and extremely well laid out inside, plus they have an advantage of mostly favoring thumbscrew-type fasteners internally.

The Define R6 standard model is what I've currently got, it has 1 dedicated external 5.25" slot and bracket, includes 6 universal 3.5"/2.5" brackets with mounting points for up to 5 more, and includes 2 dedicated 2.5" brackets with mounting points for up to 2 more.

The most recent model, the Define 7, has an "XL" model which has two external 5.25" mounts, and can house up to 18 universal 3.5"/2.5" brackets, and 5 dedicated 2.5" brackets.

Combine a Define-series case with a good modular PSU from "be quiet!", a beefy Noctua CPU cooler so you can keep the fan RPMs down, and a high-diameter case fan or two, and you'll end up with a machine that's clean inside, and dead silent outside.

I first went with Fractal Design when I built a machine back in 2015, and have stuck with them ever since because of just how trouble-free they've been.

Edit: For reference, my current machine has an AMD Ryzen 9 3950X (16 cores, 32 threads, Zen 2) and a Zotac RTX 3080 GPU. Even running full tilt on benchmarks, I can't even hear the machine running when combined with all the above bits.