here are the settings below i use for space harrier, which for me work very well and stop autocentering. if these settings dont work for you perhaps you need to set your up/down/left/right controls in mame for the game space harrier to somewhere on your gamepad which isnt analog (ie. dont play space harrier with your gamepad's analog thumbstick, use the regular digital directional pad instead).. or, if u do want to use the analog thumbstick, set it to 'digital mode' instead