I've never had any problem getting software to run with the exception of Roxio Easy Media Creator 8. Unfortunately, this software is so deeply rooted into the OS, I think that was the problem. Plus, I am running Windows 7 64-bit. I think it would work on Windows 7 32-bit. As a matter of fact, I might try to install it in Windows 7 32-bit in Virtual PC just to see what happens. BTW, XP Mode in Virtual PC works pretty good too. Another cool thing you can do with Virtual PC is... I have taken a Ghost image of my Windows XP install and converted it to VHD (Virtual Hard Disk) that Virtual PC uses. I can boot my old PC just like the day the image was taken. Unfortunately, with the detected hardware change, I only get three days before I must reactivate. Since it's an OEM license, I cannot transfer the license.